The MAN1B1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ERMAN1, and MAN1B1. This antibody recognizes Human, and Mouse antigen. The MAN1B1 Antibody has been validated for the following applications: Western Blot.
Description
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544].Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699].Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309]